UCSF home page UCSF home page About UCSF Search UCSF UCSF Medical Center
  HomeContact Us SFVANCIRE
Recent Publications


2001 Ying W, Sevigny MB, Chen Y, Swanson RA: Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death. Proc Natl Acad Sci , 98:12227-12232
2002 Anderson CM, Norquist BA, Vesce S, Nicholls DG, Soine WH, Duan S, Swanson RA: Barbiturates induce mitochondrial depolarization and potentiate excitotoxic neuronal death. J Neuroscience, 22:9203-9209
2003 Duan S, Anderson CM, Keung E, Farrell K, Chen Y, Chen Y, Swanson RA: P2X7 receptor-mediated release of excitatory amino acids from astrocytes. J Neuroscience, 23:1320-1328M
2003 Garnier P, Ying W, Swanson RA : Ischemic preconditioning by caspase cleavage of Poly(ADP-ribose) polymerase-1. J Neuroscience 23:7967-7973 {with editorial comment on p. 7964}
2003 Suh SW, Aoyama K, Chen Y, Garnier P Matsumori Y, Gum E, Liu J, Swanson RA: Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia. J Neuroscience 23:10681-10690
2004 Swanson RA, Ying W, Kauppinen TM: Astrocyte influences on ischemic neuronal death. Current Mol. Med. 4:193-205
2004 Alano CC, Ying W, Swanson RA: Poly(ADP-ribose) polymerase-1 mediated cell death in astrocytes requires NAD depletion and mitochondrial permeability transition. J Biol Chem 279:18895-902
2005 Kauppinen TM, Swanson RA: Poly(ADP-ribose)polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9 - mediated neuron death. J Immunology, 15:2288-2296
2006 Kauppinen TM, Suh SW, Wiggins AK, Huang EJ, Swanson RA: Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated proteins 1/2 . Proc Natl Acad Sci 103:7136-41
2006 Alano, CC, Kauppinen TM, Swanson RA: Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc Natl Acad Sci 103:9685-90
2006 Aoyama K, Suh SW, Hamby AM, Liu J, Chan WY, Chen Y, Swanson RA: Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nature Neuroscience, 9:119-126
2007 Hamby AM, Suh SW, Kauppinen TM, Swanson RA: Use of a poly(ADP-ribose) polymerase inhibitor to suppress inflammation and neuronal death after cerebral ischemia-reperfusion. Stroke, 38:632-62
2007 Suh SW, Bergher JP, Anderson CM, Treadway JL, Fosgerau K, Swanson RA: Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with the glycogen phosphorylase inhibitor CP-316,819. J Pharm Exp Therap, 321:45-50
2007 Suh SW, Gum ET, Hamby AM, Chan PH, Swanson RA: Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase. J Clin Invest, 117:910-918
2008 Kauppinen TM, Higashi, Y, Suh SW, Escartin C, Nagasawa K, Swanson RA: Zinc triggers microglial activation. J Neuroscience. 28:5827-35
2008 Suh SW, Hamby AM, Gum ET, Shin BS, Won SJ, Sheline CT, Chan PH, Swanson RA: Sequential release of nitric oxide, zinc, and superoxide in hypoglycemic neuronal death. J Cereb Blood Flow Metab, (in press)
2008 Suh SW, Shin BS, Ma H, Van Hoecke M, Brennan AM, Yenari MA, Swanson RA: Glucose and NADPH oxidase drive neuronal superoxide production during ischemia-reperfusion. Annals of Neurology, (in press)

For questions or comments, please contact: Ari Berman
Last modified: